Optic nerve head three-dimensional shape analysis
نویسندگان
چکیده
منابع مشابه
Optic nerve head drusen.
Optic disc drusen are congenital and developmental anomalies of the optic nerve head seen commonly in clinical practice, often as an incidental ophthalmologic finding during routine exams. Optic disc drusen are a form of calcific degeneration in some of the axons of the optic nerve. Visual acuity is often not affected but the visual fields of these patients can be abnormal and deteriorate over ...
متن کاملHigh resolution three-dimensional reconstruction of the collagenous matrix of the human optic nerve head.
Glaucoma is the second most common cause of blindness worldwide, leading to irreversible loss of vision. Prior studies indicate that ocular pressure-induced displacement of the lamina cribrosa (LC) may be responsible for retinal ganglion cell axon damage inside the neural canal. We present a novel approach to imaging the entire lamina cribrosa and the scleral canal at high lateral and axial res...
متن کاملThree-dimensional reconstruction of normal and early glaucoma monkey optic nerve head connective tissues.
PURPOSE To introduce high-resolution, digital three-dimensional (3-D) reconstruction of the connective tissues of the optic nerve head (ONH). METHODS Trephinated ONH and peripapillary sclera from both eyes of three monkeys with early glaucoma (EG; one eye normal, one eye given laser-induced EG) were embedded in paraffin and serial sectioned at 3-mum thickness from the vitreous surface through...
متن کاملIn vivo optic nerve head biomechanics: performance testing of a three-dimensional tracking algorithm.
Measurement of optic nerve head (ONH) deformations could be useful in the clinical management of glaucoma. Here, we propose a novel three-dimensional tissue-tracking algorithm designed to be used in vivo. We carry out preliminary verification of the algorithm by testing its accuracy and its robustness. An algorithm based on digital volume correlation was developed to extract ONH tissue displace...
متن کاملQuantitative analysis of three-dimensional fibrillar collagen microstructure within the normal, aged and glaucomatous human optic nerve head
The aim of this study was to quantify connective tissue fibre orientation and alignment in young, old and glaucomatous human optic nerve heads (ONH) to understand ONH microstructure and predisposition to glaucomatous optic neuropathy. Transverse (seven healthy, three glaucomatous) and longitudinal (14 healthy) human ONH cryosections were imaged by both second harmonic generation microscopy and ...
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ژورنال
عنوان ژورنال: Journal of Biomedical Optics
سال: 2018
ISSN: 1083-3668
DOI: 10.1117/1.jbo.23.10.106004